Programme & Speakers
Programme
In this section you will find the complete final programme of the Conference.
Programme of the
49th Annual Conference on Yeast
Tuesday 13th May 2025
13:30-
Transport from Bratislava to Smolenice by conference bus
11:00-16:30
Registration
15:00-16:30
Coffee, tea & snacks
16:30-16:45
49th Annual Conference on Yeasts - Opening Ceremony
Milan Čertík
 (Slovakia)
Kocková-Kratochvílová Memorial Lecture
Chairperson:
Milan Čertík
(Slovakia)
16:45-17:30
Invited Speaker:
Diethard Mattanovich
 (Austria)
The three lives of methylotrophic yeasts in biotechnology
Biotechnology of Yeasts
Chairpersons:
Milan Čertík
(Slovakia),
Ivana Márová
(Czechia)
17:30-18:00
Invited Speaker:
Iva Pichová
 (Czechia)
Insect pheromone production in yeast
19:00-
Welcome reception
Open-air barbecue with folk music (folklore ensemble Gymnik, Slovakia) and local Little Carpathian wines.
Wednesday 14th May 2025
08:00-09:00
Breakfast
Biotechnology of Yeasts
Chairpersons:
Milan Čertík
(Slovakia),
Ivana Márová
(Czechia)
09:00-09:30
Invited Speaker:
Gerhard Sandmann
 (Germany)
Metabolic engineering of high-yield carotenoid yeast strains with the basidiomycetous yeast Xanthophyllomyes as an example
09:30-09:45
Magdalena Rakicka-Pustułka
 (Poland)
Biotechnological production of kynurenic acid using yeast
09:45-10:00
Iris Cornet
 (Belgium)
Starmerella bombicola vs. Candida tropicalis, who wins in long-chain dicarboxylic acid production?
10:00-10:15
Ludwika Tomaszewska-Hetman
 (Poland)
α-Ketoglutaric acid production by Yarrowia lipolytica yeast
10:15-10:30
Peter Gajdoš
 (Slovakia)
Special lipids produced by Yarrowia lipolytica: acetylated diacylglycerols
10:30-10:45
Alex Kruis
 (Slovenia)
Rational strain design at Acies Bio: Rewiring Yarrowia lipolytica for enhanced carotenoid production
10:45-11:10
Coffee break
Biotechnology of Yeasts
Chairpersons:
Milan Čertík
(Slovakia),
Ivana Márová
(Czechia)
11:10-11:25
Volkmar Passoth
 (Sweden)
Oleaginous yeasts for biochemicals, food and a safe environment
11:25-11:40
Harald Pichler
 (Austria)
Greasing the product portfolio of Komagataella phaffii
11:40-11:55
Dorota Kregiel
 (Poland)
Metschnikowia sp. in a wide range of "green" applications
11:55-12:10
Dana Byrtusová
 (Norway)
Yeast-derived single-cell oil for coatings: Upscaling fermentation and extraction
12:10-12:25
Zbigniew Lazar
 (Poland)
Hexokinase at the Helm - Steering sugar metabolism in Yarrowia lipolytica
12:25-12:40
Jolanta Mierzejewska
 (Poland)
Food-borne yeasts and their extracellular vesicles as promising delivery systems for bioactives in the human gut
12:40-12:55
Matthias Steiger
 (Austria)
Harnessing yeast-derived VLPs for enzyme encapsulation and biocatalysis
13:00-14:00
Lunch
Yeast Diversity and Interaction
Chairpersons:
Renáta Vadkertiová
(Slovakia),
Matthias Sipiczki
(Hungary)
14:00-14:30
Invited Speaker:
Matthias Sipiczki
 (Hungary)
Prospects and pitfalls of phylogenomic analysis of genome sequences in yeast taxonomy
14:30-14:45
Gianluigi Cardinali
 (Italy)
Challenges, problems and solutions for environmental yeast metagenomics
14:45-15:00
Angela Conti
 (Italy)
From sequences to integers: the process of converting MinION reads into Metabarcoding data
15:00-15:20
Coffee break
Yeast Diversity and Interaction
Chairpersons:
Renáta Vadkertiová
(Slovakia),
Matthias Sipiczki
(Hungary)
15:20-15:35
Debora Casagrande Pierantoni
 (Italy)
Development of pathogenic characters among environmental isolates of Candida parapsilosis
15:35-15:50
Karin Mandl
 (Austria)
Inoculation of Starmerella lactis-condensi, Saccharomyces cerevisiae and orange wine Lee for orange sparkling wine production
15:50-16:05
Miloslava Kavková
 (Czechia)
The yeast in food matrices - friends and foes
16:30-19:00
Excursion to the mead company
Excursion to the mead (honey wine) company and mead degustation
20:00-21:00
Dinner
Thursday 15th May 2025
08:00-09:00
Breakfast
Molecular and Cell Biology of Yeasts
Chairperson:
Silvia Bágeľová-Poláková
(Slovakia)
09:00-09:30
Invited Speaker:
Frank Uhlmann
 (United Kingdom)
Why does a chromosome look like a chromosome?
09:30-09:50
Václav Brázda
 (Czechia)
Yeast-based investigation of G-quadruplex influence on human transcription factors activity
09:50-10:10
Jan Paleček
 (Czechia)
Factors facilitating SMC loading: SAGA targeting of SMC5/6
10:10-10:25
Karol Kramarz
 (Poland)
Recombination at difficult-to-replicate sites is controlled by SUMO chains in Schizosaccharomyces pombe
10:25-10:40
Nina Mayerová
 (Slovakia)
Dbl2 interacts with helicases and an endonuclease to maintain the integrity of repetitive regions
10:40-11:00
Coffee break
Molecular and Cell Biology of Yeasts
Chairperson:
Katarína Gaplovská
(Slovakia)
11:00-11:30
Invited Speaker:
Shigeaki Saitoh
 (Japan)
Cellular response to starvation in the fission yeast Schizosaccharomyces pombe
11:30-11:50
Martin Lukačišin
 (Slovakia)
Investigating growth sensitive processes with isogrowth profiling
11:50-12:05
Ireneusz Litwin
 (Poland)
Arsenic genotoxicity in yeast: Non-lethal doses elicit global DNA damage responses while inducing only localized DNA lesions
12:05-12:20
Miroslava Požgajová
 (Slovakia)
Involvement of TORC2 signaling in cell response to acrylamide-mediated stress in Schizosaccharomyces pombe
12:30-13:30
Lunch
Molecular and Cell Biology of Yeasts
Chairperson:
Roman Holič
(Slovakia)
13:30-13:50
Toon De Kroon
 (The Netherlands)
New insights into the regulation of membrane lipid acyl chain length
13:50-14:05
Jiří Stříbný
 (Switzerland)
Perilipin 3 protein recognizes DAG-containing membranes by its conserved PAT domain
14:05-14:20
Dominik Šťastný
 (Slovakia)
Human parasite lipid transfer proteins: The yeast story
14:20-14:35
Angelo Slade
 (Canada)
Is mRNA translation compromised in sideroblastic anemia, B-cell immunodeficiency, periodic fevers, and developmental delay (SIFD)?
14:35-14:50
Viktor Stolc
 (United States)
Stress-activated positive holes in rocks as catalysts of RNA-based mutagenesis in yeast
14:50-15:10
Coffee break
Poster Highlights - Session of young scientists/students
15:10-16:00
Chairpersons:
Felix Fronek
(Austria),
Ondrej Preťo
(Slovakia)
Nela Gerspitzerová
 (Czechia)
Isolating biologically active beta-glucans from the red yeast Rhodotorula toruloides
Marek Lúčan
 (Slovakia)
Refinement of ergosterol biosynthetic pathway to enhance squalene production in Rhodotorula toruloides
Pavlína Sikorová
 (Czechia)
Using microbial extracts to create cosmetics products
Lucia Dzurická
 (Czechia)
Functionalized biopolymer-based nanofibres with antifungal efficacy
Kristína Alföldiová
 (Slovakia)
Analysis of lipid metabolism in yeasts of the genus Magnusiomyces
Veronika Novysedláková
 (Slovakia)
Genetic interactions between dbl2 and genes involved in transfer to nuclear pore complexes
Laura Olívia Karika
 (Slovakia)
Characterization of functional interactomes of G-patch proteins in the fission yeast Schizosaccharomyces pombe
Ema Lisá
 (Slovakia)
Effect of non-thermal plasma on mitochondrial components in yeast
Dominika Piatrová
 (Slovakia)
The role of rdh54 and dbl2 genes in meiotic recombination of Schizosaccharomyces pombe
Libuše Kratochvílová
 (Czechia)
Effect of G-quadruplex structures on the transcription activity of oncologically important proteins
Andrea Valentová
 (Slovakia)
Substitution of conserved Ser31 in the Rim1 protein affects its DNA-binding properties in vitro
Poster session
16:00-18:00
19:00-
Special Conference dinner with live music (Los Saranchos)
Friday 16th May 2025
08:00-09:00
Breakfast
09:00-10:00
ACY Scientific Committee Meeting
09:00-10:00
Check-out of participants
10:20-10:40
49th Annual Conference on Yeasts - Closing Ceremony with awards presentation
Milan Čertík
 (Slovakia)
11:10-
Transport from Smolenice to Bratislava by conference bus
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Speakers
Discover the invited and registered speakers shaping this year's conference.

Keynote speaker
Anna Kocková-Kratochvílová Memorial Lecture
Diethard Mattanovich
Austria
The three lives of methylotrophic yeasts in biotechnology
Diethard Mattanovich is Professor of Microbial Biotechnology and Head of Department of Biotechnology and Food Science at BOKU University in Vienna. His research interests are centered on yeast biotechnology, with a strong focus on methylotrophic yeasts, their genetics and metabolism, and modes of engineering them to produce valuable goods in a sustainable way. Especially their ability to assimilate single carbon substrates like methanol, formic acid and CO2 raises promises for circular production of food, feed, and materials. Diethard Mattanovich is a member of the International Commission on Yeast (ICY) which he has chaired from 2021-2024.
Invited speakers
Iva Pichová
Czechia
Insect pheromone production in yeast
Iva Pichová is a biochemist at the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences. Her research group focuses on the functional characterization and evolution of enzymes involved in fatty acid biosynthesis across diverse insect species and pathogenic Candida species. Through a combination of bioinformatic analysis, functional expression of enzymes in yeast, and the analysis of enzyme products by GC-MS, they have identified novel fatty acid desaturases (FADs) and reductases (FARs) that regulate the biosynthesis of fatty acid derivatives in these species. Employing AlphaFold and rational mutagenesis of FADs and FARs, the key structural motifs contributing to specificity of these enzymes were identified. These results provide an effective approach for engineering of enzymes with unique properties for biotechnological applications.
Shigeaki Saitoh
Japan
Cellular response to starvation in the fission yeast Schizosaccharomyces pombe
After receiving Ph.D. degree from Kyoto University, Japan, under the supervision of Prof. Mitsuhiro Yanagida, Prof. Saitoh worked as a research associate in Paul Russell's laboratory at The Scripps Research Institute, CA, USA, studying the cellular response to DNA-damaging stress using the fission yeast Schizosaccharomyces pombe. Since moving to Kurume University, Prof. Saitoh have been studying the molecular and genetic mechanisms by which fission yeast cells cope with nutrient starvation stress.
Gerhard Sandmann
Germany
Metabolic engineering of high-yield carotenoid yeast strains with the basidiomycetous yeast Xanthophyllomyes as an example
Gerhard Sandmann, retired professor, still affiliated to the Institute of Molecular Biosciences of Goethe University Frankfurt. His research is focused for over 40 years on the biosynthesis of carotenoids in different organisms including plants, bacteria and fungi. More than 300 publications resulted from these activities. The work covers the elucidation of pathways with their enzymes and the molecular genetics including functional genomics. The cloning of the carotenogenic genes involved laid the basis for the heterologous enzyme synthesis to study catalytic mechanisms and substrate/product specificity which enables pathway constructions and for the metabolic engineering of carotenoid production systems. During the last years, the biotechnological focus was on the red yeast Xanthophyllomces dendrorhous also known as Phaffia rhodozyma. This yeast was genetically engineered for high-yield production of different carotenoids.
Matthias Sipiczki
Hungary
Prospects and pitfalls of phylogenomic analysis of genome sequences in yeast taxonomy
Matthias Sipiczki is Professor of Microbial Genetics at the University of Debrecen. He founded the University's Department of Genetics and Applied Microbiology and was head of the department for more than 20 years. He was also Dean of the Faculty of Science and Technology and Vice-Rector of the University. His research interests are mainly in yeast biology, genetics, molecular taxonomy and phylogenetics. His research has also focused on wine yeasts and the use of antagonistic yeasts in biological control.
Frank Uhlmann
United Kingdom
Why does a chromosome look like a chromosome?
Frank Uhlmann was born and grew up in Germany. He studied biochemistry and physiological chemistry at the University of Tübingen before joining Jerry Hurwitz's laboratory at Memorial Sloan-Kettering Cancer Center in New York for his PhD studies. Frank then moved to the Institute of Molecular Pathology in Vienna to work as a postdoc with Kim Nasmyth. In 2000, he established a research laboratory at what was then the Imperial Cancer Research Fund in London. He has remained there ever since, while the institute became part of Cancer Research UK and now The Francis Crick Institute. His work on chromosome segregation was recognised with the EMBO Gold Medal in 2006.
Speakers
Václav
Brázda
Czechia
Dana
Byrtusová
Norway
Gianluigi
Cardinali
Italy
Debora
Casagrande Pierantoni
Italy
Iris
Cornet
Belgium
Toon
de Kroon
The Netherlands
Peter
Gajdoš
Slovakia
Ken
Ishikawa
Japan
Miloslava
Kavková
Czechia
Karol
Kramarz
Poland
Dorota
Kregiel
Poland
Aleksander
Kruis
Slovenia
Zbigniew
Lazar
Poland
Ireneusz
Litwin
Poland
Martin
Lukačišin
Slovakia
Karin
Mandl
Austria
Nina
Mayerová
Slovakia
Jolanta
Mierzejewska
Poland
Jan
Paleček
Czechia
Volkmar
Passoth
Sweden
Harald
Pichler
Austria
Miroslava
Požgajová
Slovakia
Magdalena
Rakicka‑Pustułka
Poland
Angelo
Slade
Canada
Dominik
Šťastný
Slovakia
Matthias
Steiger
Austria
Jiří
Stříbný
Switzerland
Ludwika
Tomaszewska‑Hetman
Poland
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